Morgellons disease 


Crown Gall disease in plants is a transgenic disease induced by Agrobacterium. The Agrobacterium finds a wound on the plant to enter and then infects the cells by Horizontal Gene Transfer. A Eukaryote is any organism whose cells contain a nucleus, mammals have Eukaryotic cells. Agrobacterium and Bartonella are both Rhizobiales order bacteria and are very similar.

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 Prokaryotic cells do not have a nucleus and these are bacteria. Prokaryotic cells use Horizontal Gene Transfer normally among themselves to reproduce. Currently scientists are aware that there are only two bacteria and a couple viruses that are capable of Horizontal Gene Transfer from a Prokaryotic cell into Eukaryotic cells. That is to transfer genes from a bacterial genome into , a persons genome. Besides Agrobacterium the other bacteria capable of this is Bartonella.

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Agrobacterium is naturally occurring and because of the ability of Horizontal Gene Transfer it is selected as the gene transfer method of choice in genetic engineering.

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 When Agrobacterium undergoes a gene splicing operation they will splice a T-section of DNA into the Agrobacterium DNA. The end product results in a bacteria that can transfer gene’s from other organisms into our own Eukaryotic cells.

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 The T-DNA section to be inserted in the Agrobacterium’s  plasmid has different components. It sometimes uses a gene marker for fluorescence so that the research scientist can see those markers under a microscope as reference points. A selection gene for antibiotic resistance is also sometimes used and when treated with antibiotics the Agrobacterium that did not receive the gene transfer die, this is done to select out the successfully DNA transferred  Agrobacterium. Commonly used is a Cauliflower Mosaic virus as a promoter gene to keep it turned on, so the plasmid does not reject the target gene to be transferred because viruses can force the target cells to accept the genetic material. It uses another gene as a stop sign to tell it when to stop the Horizontal Gene Transfer.

.    Agrobacterium is released in nature with a transgenic plasmid is capable of passing varied traits to other bacteria so the actual pathogen that causes Morgellons  is yet to be classified but it is safe to say it is a Rhizobiales order bacteria, you can still treat it. It should also be noted that bacteria in nature are in constant evolution so subsequent type pathogens of various strains are possible. In Morgellons there is fiber growth in the tissues of infected people. The fibers have been determined to be keratanized cells by Charles Holman Foundation researchers, your fingernails and toenails are keratinized cells.  There is also a collagen content in the fibers.

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​  When any cells grow in our bodies it is because the information found in the genetic material, DNA, has defined the instruction for exactly what is created. When fibers grow out of someone then the conclusion should be that the genome has been altered and a gene has been inserted from another organism . The MD producing gene is using building blocks found in our bodies. Agrobacteriium is a naturally occurring bacteria and is altered to become a tool for genetic engineering. Agrobacterium causing Crown Gall disease in plants shows creating a tumor tissue in the plant in a gall shape that sequester bacterial concentrations. This similarly created genetic callus material is what we see in Morgellons presentations as the hard debris that come from lesions and out of other areas on the skin. The fibers grow because of a transgenic structure using our bodies building materials. They usually grow out of areas where the genetically produced tumor tissue material has infected.

The genetic engineering process using Agrobacterium with T-DNA has yielded a bacteria that in itself, or by gene transfer into another bacteria such as Bartonella, so that bacteria now  becomes the MD pathogen that causes MD. The specific gene that causes the fiber growth is not yet known perhaps from a fungus. There is also the possibility that Bartonella receives a gene from another infective pathogen inside the body and then uses it's ability to transfer that into human cells .
The credible evidence strongly suggests that Morgellons Disease is a manifestation of genetic manipulation from a Rhizobiales order bacteria with an unknown genetic variant. Since Agrobacterium and Bartonella are so closely related the exact pathogen could be a Bartonella like organism. They are Rhizobiales order alpha proteobacteria. They are gram-negative and share some genes. Bartonella is very difficult to remove from the body. Morgellons typically exhibits this quality of being very difficult to remove from the body as well. In my research I looked at pictures of Bartonella lesions and MD lesions and found them to be very similar. In Bartonella you get "red track marks" on the skin, you also get these in MD. It is not only that the MD pathogen is tenacious like Bartonella and has very similar lesions but it is also that is produces the internal growth of tumor tissue similar to the tumor tissue in Crown Gall disease.

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http://www.creative-bioarray.com/Human-Epidermal-Keratinocytes-fetal-HEK-f-CSC-7790W-item-1845.htm

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"The epithelial layer of the skin provides an essential function as a protective barrier against insult from the outside environment. The major cell type in this layer is keratinocytes which consists around 85% of living epidermal cells. Keratinocytes are the cells of stratified squamous epithelia. It is so named because its most abundant protein is keratin."


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http://f1000research.com/articles/2-118/v1

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​"Morgellons disease (MD) is a term that has been used in the last decade to describe filaments that can be found in human epidermis. It is the subject of considerable debate within the medical profession and is often labeled as delusions of parasitosis or dermatitis artefacta. This view is challenged by recent published scientific data put forward between 2011-2013 identifying the filaments found in MD as keratin and collagen based and furthermore associated with spirochetal infection."

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The word association is key here, an "association"

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​A study of genetics would reveal that to get something novel to grow from the skin is a form of Gene Expression, to accomplish that an adjustment of cellular DNA is required.

There are only two bacteria known to science that can accomplish this and one of them is Agrobacterium, that is why it is used to GM the food supply, the other is Bartonella. Borrelia can not accomplish this as noted in the scientific literature.

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http://microbewiki.kenyon.edu/index.php/Bartonella_henselae​

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​"Bartonella are the only bacteria able to produce angiogenic tumors in humans, very much like the Agrobacterium species that produce tumors in plants"


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http://www.ncbi.nlm.nih.gov/pubmed/21844337


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"Conjugative DNA transfer into human cells by the VirB/VirD4 type IV secretion system of the bacterial pathogen Bartonella henselae."

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​The conclusion based on the above is that Bartonella or a Bartonella like organism has adjusted the cellular genome of the Keratinocytes causing them to produce keratin fibers.

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​ "B. henselae infection significantly induces the expression of the cytokeratin genes."

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"Transcriptional Regulation of Keratin Gene Expression"

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http://www.ncbi.nlm.nih.gov/pubmed/26000974

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​"Competence of Cimex lectularius Bed Bugs for the Transmission of Bartonella quintana, the Agent of Trench Fever."

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​  In understanding genetics we should understand the concept of the “Fluid Genome”.  Looking at Cancer then Cancer is the result of a readjustment of cellular DNA. This readjustment is caused because DNA responds substantially to the environment it is in. Environmental toxins or toxins excreted by pathogens or radiation exposure can cause a readjustment of cellular DNA and this results in free cell proliferation of mutated cells which is Cancer. A very good understanding of the "Fluid Genome" can be found here;

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http://natureinstitute.org/txt/st/mqual/genome_remodeling.htm#fluid_genome1

. . Geneticists used to think that DNA was set until the mid 80's or so and then the world of genetics changed dramatically as the concept of the "Fluid Genome" was accepted.  DNA responds substantially to it’s environment. Typically a person who has Lyme disease and carries a variety of co-infections is a good candidate to develop MD. These collections of infections will infect the immune system and have many strategies to make the immune system dysfunctional. Agrobacterium is generally is thought of as an opportunistic infection that will become symptomatic if the immune system cannot cope with it. The MD pathogen also forms a symbiotic relationship with whatever co-infections a person carries. They work together to systematically defeat the body’s defenses and protect themselves from any treatment. During a bacterial infection the symptoms a person experiences are from the exotoxins that the bacteria release. When a pathogenic bacteria is killed it releases a flood of endotoxins and this is responsible for the Herxheimer reaction a person will experience during recovery.
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​. In order to treat MD you need to remove all pathogens from your body. Also to remove all the toxinsthey generated and repair the DNA damage that was done by the transgenes. Also to repair the DNA damage done by the altered environment in a person that disrupted the cellular DNA because the DNA adjusted to it’s environment. Some examples of things that alter human DNA aresynthetic pharmaceuticals, hormone disruptors and industrial chemicals and other environmental toxins.

​. ​ "Antibiotics Kill Bacteria By Damaging Their DNA"

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www.medicalnewstoday.com/articles/244435.php
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 Unfortunately synthetic antibiotics are not intelligently selective and they also damage human DNA;
​.  http://www.collective-evolution.com/2013/09/18/a-horrifying-cause-of-autism-dna-damage-from-synthetic-antibiotics/

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“A team of scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University has discovered why long-term treatment with many common antibiotics can cause harmful side effects.”


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http://www.sciencedaily.com/releases/2013/07/130703160623.htm

.   In MD patients something that should be done is to remove toxins from the body but also steps should be taken to repair DNA.
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​ Noteworthy is the ability of plant medicines to do this. . “Cat’s claw repairs DNA damage caused by chemotherapy”
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http://www.nyrnaturalnews.com/herbal-remedies/2012/07/cats-claw-repairs-dna-damage-caused-by-chemotherapy/

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Another very noteworthy study determines that amino acids are better at fighting infections than antibiotrics. Morgellons is extremely resistant to ABX as are many of the Lyme co-infections. 

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http://www.sciencedaily.com/releases/2011/06/110608093745.htm

.   ​. The beauty of using plant medicines to treat infections like Lyme disease and MD is that millions of years of evolution has allowed the constituents to be intelligently selective. As plant medicines have shown themselves to be inherently intelligent in killing pathogenic microbes and not harming good ones, through DNA identification, then I would assert that this relatively unexplored ability also extends to identifying the MD pathogens DNA. Attacking that pathogenic DNA and as well setting up an environment where it will be detoxed. Enough plant medicines need to be used in an MD patient to accomplish this and typical herbal protocols are inadequate in this regard.

​ www.sactorose.org/ipm/83crowngall.htm

. "DISEASE CYCLE: The bacteria causing the disease are soil born and can survive in soils for many years. When roses areplanted in infested soil any wound sites on the roots or crown offer points of entry for the bacteria. Once in the host the tumor inducing principle carried on a small circular portion of DNA is incorporated into the plant cell and a overgrowth begins to form. In some plants the bacteria can be systemic and galls may begin to form at many sites on the plant. As the galls develop callus tissue is laid down which is susceptible to other types of breakdown, decay or sloughing. In this way the soil around a plant can become infested with the bacteria." This sounds familiar when considering that the lesions in MD spread in a similar fashion; "In some plants the bacteria can be systemic and galls may begin to form at many sites on the plant." ​ It is why the MD lesions don't heal, because under the skin there is a deposit of crown gall tumor tissue and it will never heal unless that is completely removed. It can be removed over time using the organic acids found in plant medicines. Unfortunately there are many theories on the internet that have no scientific basis that fault a variety of things for  MD and this doesn't help the MD community. There are top level scientists that have made some very credible assertions however.
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Here is a reprinted article;

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 Reuters Health News - January 31, 2001 -Emma Patten NEW YORK - "Tumor-Causing Plant Bacteria May Infect Human Cells"


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A soil bacterium that causes lumpy tumors on plants may be able to 'jump kingdoms' and insert its tumor-causing DNA into human cells, new research findings suggest. The bacterium, called Agrobacterium tumefaciens, contains a small piece of DNA that can insert itself into the DNA of a host cell and initiate a tumor. Agrobacterium is already known to cause plant tumors, but researchers wanted to test whether the bacterium could similarly insert its DNA into human cells. Dr. Vitaly Citovsky from the State University of New York, Stony Brook, and colleagues found that the plant bacterium was able to attach to human cells and insert its DNA into human cells just as it does with plant cells. Whether Agrobacterium is dangerous to humans is unclear, however. "Here (insertion of DNA into) human cells has been observed in laboratory conditions; whether it may be relevant biologically in nature remains unknown," the researchers note in the current early edition of the Proceedings of the National Academy of Sciences. "Our experiments were done under laboratory conditions," Citovsky told Reuters Health. "In nature, I do not believe Agrobacterium represents a danger. However, for peoplewho work with large concentrations of this bacterium, for example researchers or certain agricultural workers who deal with heavily infected plants, it may be prudent to be careful or at least aware,'' he said. One implication of this study, said Citovsky, is the potential for genetic flow between bacteria and animals. Another implication is that the basic biochemical and cellular reactions involved in the Agrobacterium-plant cell interaction probably exist in the animal kingdom as well. "Presently, it appears that Agrobacterium is the only example of trans-kingdom DNA transfer," Citovsky said. "I do not rule out other possibilities but there are no data. Of course, what can be done once, can almost always be done again," he added.”
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​ Another very credible source is the Institute for Science in Society;

. Dr . Mae-Wan Ho is a geneticist known for her critical views on genetic engineering and neo-Darwinism. Ho has authored or co-authored a number of publications, including 10 books, such as The Rainbow and the Worm, the Physics of Organisms,Genetic Engineering: Dream or Nightmare? and Living with the Fluid Genome.She also founded the Institute for Science in Society.
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Professor Joe Cummins Professor Emeritus of Genetics University of Western Ontario Education,PhD University of Western Ontario ,Canada-BS , Horticulture Washington State University, PhD , Cellular Biology,University of Wisconsin These two renowned scientists authored this very good paper as well as others on genetic engineering and MD; .
​  www.i-sis.org.uk/agrobacteriumAndMorgellons.php . "Agrobacterium & Morgellons Disease, A GM Connection?"

When I created a protocol to treat my own chronic Lyme disease and Morgellons disease the DNA aspect was well considered this included consideration of the "Fluid Genome".   NOTE *For anyone wanting an in depth understanding of Agrobacterium mediated gene transfer then here is the pdf which is 773 pages long and is edited by Citovsky, because he is a world authority on the subject. There are about 50 contributing authors. There are very many descriptions of Agrobacterium transferring T-DNA into eukaryotic cells. A Eukaryote is any organism whose cells contain a nucleus, mammals have Eukaryotic cells. 

. About the Editors:

. Dr. Tzvi Tzfira is an Assistant Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of Michigan. Dr. Vitaly Citovsky is a Professor in the Department of Biochemistry and Cell Biology at Stony Brook University.
. www.stonybrook.edu/commcms/biochem/citovsky/60.pdf

. From page 173, there are numerous explanations of this in this document.

. "Abstract; Agrobacterium is a bacterial plant pathogen capable of transferring a specific fragment of DNA, called the T-DNA, into plants and other organisms. Once in a eukaryotic cell, the T-DNA moves to the nucleus and integrates into the genome at an essentially random location. T-DNA integration generally leads to tumor formation in the plant host, and Agrobacterium’s ability to transfer DNA has been adapted as an important tool for mutagenesis and genetic engineering of plants and fungi. Agrobacterium tumefaciens C58 was the first species of Agrobacterium to have a fully-sequenced genome, and the sequence data are catalyzing expansion of A. tumefaciens research beyond its traditional focus on plant pathogenesis and T-DNA transfer. This chapter reviews many of the findings of the original genome publications and discusses many new insights derived from the availability of the genome sequence."  


Repairing your DNA

As the infections will be removed by the constituents of the protocol and the large amount of amino acids will help to repair the disease states that make you more vulnerable to infection then the remaining question is what is left to do to repair DNA.

In keeping with the understanding of the Fluid Genome, that DNA responds to its environment substantially, It should be possible to put healthy influences in play in your body to influence adjustment of your DNA to a healthy state.

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Cats claw has been shown to repair DNA damage from Chemotherapy as mention already on this page with a link provided. It would not be unreasonable to assume that many plant medicines do this.

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http://www.nyrnaturalnews.com/herbal-remedies/2012/07/cats-claw-repairs-dna-damage-caused-by-chemotherapy/

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"Cat’s claw repairs DNA damage caused by chemotherapy"



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www.ncbi.nlm.nih.gov/pubmed/21844337

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"Bartonella henselae can transfer a cryptic plasmid occurring in the bartonellae into the human endothelial cell line"


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